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Zopiclone for Mental Illness? - Most people are unfamiliar with an active ingredient called “Zoplicon." However, anyone who has prescribed medication with this active ingredient would like to find out more. The fact that the active ingredient Zopiclone 7.5 mg belongs to cyclopyrrolones or the GABA receptor agonists says nothing to a medical layperson. Zopiclone is considered a sedative that belongs to a new generation of sedatives - the so-called Z-drugs. They were named after the first letter of the appropriate drug group.
It is more interesting that Zopiclone in lower doses helps fall asleep ( sleeping pill ), but it can force sleep for several hours in higher doses. In addition, these drugs act anxiolytic (anxiolytic ), antispasmodic (anticonvulsant ), and relaxes the muscles. The indication for the use of Zopiclone is a short-term treatment of insomnia in adults - short-term, transient, chronic with accompanying problems with falling asleep, low sleep, early morning awakening.
The use of benzodiazepines and substances similar to them is indicated in severe disorders, which causes severe exhaustion in the patient and the inability to function normally.
The effect of Zopiclone 7.5 mg in the CNS is similar to that of gamma-aminobutyric acid or GABA. The reason for this is simple: Zopiclone enhances the effects of GABA, which the organism can produce itself. GABA is one of the messenger substances (neurotransmitters) with either an inhibiting or activating effect in the CNS. This function is disturbed in the presence of sleep disorders.
The constant alternation between being awake and sleeping is no longer given in the usual manner due to an imbalance of different messenger substances. The administration of Zopiclone strengthens the effect of the inhibiting gamma-aminobutyric acid, the readiness for sleep is promoted.
Zopiclone is used orally.
The treatment period is usually up to 2 weeks with a maximum of 4 weeks, including the dose reduction period. In individual cases, it may be necessary to extend the use of Zopiclone beyond the maximum period. Extending the duration of use should be supported by reassessing the patient's condition.
Zopiclone is used immediately before bedtime.
Usual doses (daily) in adults: Zopiclone 7.5 mg.
In patients with hepatic insufficiency, chronic respiratory failure, and the elderly, treatment should be started at half the usual adult dose. People with known renal insufficiency should start treatment with half of the dose recommended for adults (despite no evidence of accumulation of Zopiclone and its metabolites).
This medicine with the advantages can have side effects that vary from person to person.
Most Common (may affect up to 1 in 10 people):
Some serious side effects that might occur:
Stop taking Zopiclone and contact your doctor or go to the nearest hospital emergency department if any of the following symptoms occur:
These allergic reactions are rare but serious and may require medical attention.
Psychiatric and paradoxical reactions - Zopiclone can cause restlessness, increased excitability (agitation), irritability, aggression, delusions, outbursts of anger, nightmares, hallucinations, psychoses, inappropriate behavior, and other behavioral disorders. Continue treatment with Zopiclone off if any of these symptoms you are experiencing.
Depending on the amount of Zopiclone ingested, overdose symptoms are associated with CNS depression and range from drowsiness to coma. In mild cases, drowsiness, dizziness, confusion, lethargy have been reported.
In more severe cases, ataxia, hypotension, hypotension methemoglobinemia, respiratory depression, coma have been reported.
Zopiclone7.5 mg may interact with grapefruit juice (grapefruit flavonoids slow down the metabolism of the active substance and consequently increase its concentration). Avoid grapefruit for 4 hours before and after taking Zopiclone.
Alcohol increases the sedative and hypnotic effects of Zopiclone. Concomitant use of Zopiclone and alcohol is not recommended.
Zopiclone has a calming effect and reduces the ability to drive and use machines. There may be a risk of psychomotor disturbances (especially in combination with alcohol, drugs that depress the CNS and affect blood levels of Zopiclone).
You should not perform activities requiring mental alertness and concentration within 8-12 hours (literature discrepancy) after zopiclone administration.
Zopiclone crosses the placenta. Use during pregnancy is not recommended.
The use of Zopiclone during the last trimester and labor may be associated with the development of hypothermia, hypotension, and respiratory depression of the newborn. It is called "floppy newborn syndrome."
There is a risk of neonatal withdrawal symptoms in mothers who have used Zopiclone for a long time in the last months of pregnancy.
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